Antimigraine Drugs is a medication intended to reduce the effects or intensity of migraine headache. The drugs used in migraine therapy can be divided into two groups: agents that abort an established migraine attack and agents used prophylactically to reduce the number of migraine attacks. Migraines are different from other headaches because they occur with symptoms such as nausea, vomiting, or sensitivity to light. Some people who get migraines have warning symptoms, called an aura, before the actual headache begins.