Velpanat Tablet

Dosage Form


Active Ingredients



Chronic hepatitis C virus (HCV) infection


Natco Pharma Ltd


28 tablets in 1 bottle


Sofosbuvir (400mg) + Velpatasvir (100mg)

Pack Size PricePrice/UnitQuantity
28 Tablet/s $405.00 $14.46 /Piece
56 Tablet/s $770.00 $13.75 /Piece
84 Tablet/s $1,094.00 $13.02 /Piece
Dosage Form


Active Ingredients



Chronic hepatitis C virus (HCV) infection


Natco Pharma Ltd


28 tablets in 1 bottle


Sofosbuvir (400mg) + Velpatasvir (100mg)









 Sofosbuvir (400mg) – Velpatasvir(100mg) (Velpanat Tablets)

The U.S. Food and Drug Administration approved Velpanat Tablet to treat adult patients with chronic hepatitis C virus (HCV) both with and without cirrhosis (advanced liver disease). For patients with moderate to severe cirrhosis (decompensate cirrhosis), Velpanat is approved for use in combination with the drug ribavirin. Velpanat is a fixed-dose combination tablet containing sofosbuvir, a drug approved in 2013, and Velpatasvir, a new drug, and is the first to treat all six significant forms of HCV.

About Velpanat Tablet?

Sofosbuvir (400mg) and Velpatasvir (100mg) is a fixed-dose combination of two direct-acting antiviral that has different mechanisms of action. Sofosbuvir is a nucleotide analog NS5B polymerase inhibitor while Velpatasvir is an NS5A inhibitor. Velpanat is a new medicine used to treat hepatitis C. It is a combination pill containing sofosbuvir (sold separately as Sovaldi) plus Velpatasvir.

Each dose contains 400 mg sofosbuvir and 100 mg Velpatasvir. The medicines include the following inactive components: Copovidone, croscarmellose sodium, magnesium stearate, and microcrystalline cellulose. The drugs are film-coated with a coating material containing the following inactive ingredients: iron oxide red, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.

When is Buy Velpanat prescribed?

The combination of sofosbuvir and Velpatasvir is used alone or with ribavirin (Copegus, Rebetol, and Ribasphere) to treat chronic hepatitis C (an ongoing viral infection that damages the liver). Sofosbuvir is in a class of antiviral medicines called nucleotide hepatitis C virus (HCV) NS5B polymerase inhibitors. Buy Velpatasvir is in a group of antiviral drugs called HCV NS5A replication complex inhibitors. The combination of sofosbuvir and Velpatasvir works by stopping the virus that causes hepatitis C from spreading inside the body.

How does Buy Velpanat work?

Buy Velpanat contains two direct-acting antiviral drugs that target different steps of the hepatitis C virus (HCV) lifecycle. Sofosbuvir is a nucleotide analog HCV polymerase inhibitor, meaning it blocks the polymerase enzyme which the virus must use to reproduce. Velpatasvir is an HCV NS5A replication complex inhibitor that interferes with another protein HCV uses to replicate.

How to take Sofosbuvir – velpatasvir?

The recommended dose of this medication is one tablet taken by mouth, once daily. It is commonly taken for 12 weeks. Sofosbuvir – Velpatasvir can be taken with food or on an empty stomach. If you vomit within 3 hours of taking medicine, take another dose of the drug. If it is longer than 3 hours since you have taken medicine, do not take another tablet. Continue with your regular dose schedule. Finish all this medication, even if you have started to feel better. Many things can affect the dose of drugs that a person needs, such as body weight, other medical conditions, and other medications.

What are the precaution of Velapanat Tablets?


Interaction with alcohol is unknown. Please consult your physicain.


Velpanat Tablet is probably safe to use while pregnant.
Animal studies have shown low or no adverse effect on the fetus, however, there are limited human studies. Please consult your doctor.


A severe slowing of the heart rate (symptomatic bradycardia) may occur when the drug amiodarone, which is used to treat an irregular heartbeat, is taken with Velpanat. It is not recommended to take amiodarone and Velpanat at the same time.


Velpanat Tablet is probably safe to use during lactation. Limited human data suggest that the drug does not represent a significant risk to the baby.


Do not drive unless you are feeling well. Velpanat Tablet, when taken together with other medicines for the treatment of hepatitis c infection, may produce dizziness, blurred vision and this may affect your ability to drive.


Velpanat Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Velpanat Tablet may be needed. Please consult your doctor. Limited information is available on the use of Velpanat Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Liver SAFE

Velpanat Tablet is safe to use in patients with liver disease. No dose adjustment of Velpanat Tablet is recommended.
However, inform your doctor if you have any kidney disease as regular monitoring of liver function tests may be advised in some patients while taking this medicine.

Sofosbuvir Velpatasvir Side Effects:

Multiple clinical tests evaluated the safety and efficacy of Velpanat. When taken with ribavirin, the most common side effects are:

  • Headache
  • Tiredness
  • Anemia (low red blood cell count)
  • Nausea
  • Insomnia
  • Diarrhea

This is not an exhaustive list of all potential side effects of Velpanat. These results are mild and nothing to worry about. Please tell your doctor if you experience any adverse reaction to the medication.

What are the dosages Instruction?

Velpanat is a once-daily oral medication. A typical dose of Velpanat contains 400mg of sofosbuvir and 100mg of Velpatasvir and can be taken with or without food. Do not start taking any medications without alerting your provider while on Velpanat. Do not stop taking Velpanat or change the dose of Velpanat without talking to your provider. If you miss a dose, call your healthcare provider or pharmacist. If you take too much Velpanat, seek help at your local emergency room immediately.


Keep out of the reach of children. Store at room temperature below 30 degrees C (86 degrees F). Throw away any unused medication after the expiration date.


Most adults will recover from an acute hepatitis B infection without treatment. If the virus has been in the blood for more than 6 months, it is considered a permanent (or chronic) hepatitis B infection.

Sofosbuvir is used to treat Hepatitis C virus infection. The treatment response with Sofosbuvir (in conjunction with other drugs) varies based on baseline host and viral factors.

No. Sofosbuvir is a nucleotide polymerase inhibitor.

Why Buy Velpanat Tablet from AllDayGeneric?

  • Low prices: We sell prescription medications at low prices. A free medical consultation is included with every prescription.
  • Total privacy: We always kept your information strictly confidential.
  • Convenience: You won’t need to wait in long Queue at the pharmacy, because your medications will be delivered directly to your door.
  • Authenticity: We only sell authentic Velpanat Tablet, manufactured by Natco Pharma Ltd. A valid licensed Indian pharmacist dispenses all medications sold by AllDayGeneric.

Disclaimer: The information produced here is best of our knowledge and experience, and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

AllDayGeneric is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

AllDayGeneric does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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