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Hepcvel Tablet (Sofosbuvir and Velpatasvir)
Sofosbuvir and Velpatasvir is a drug combination of Sofosbuvir, an antiviral agent, and Velpatasvir, an NS5A replication complex inhibitor. This combination is intended to be used for the treatment of infection with the hepatitis C virus. Know about its reviews, side effects, dosage, how to work, how to take, how long does it last, side effects, dosage, and Precautions.
Sofosbuvir and Velpatasvir is a fixed-dose combination of two direct-acting antiviral that has different mechanisms of action. Sofosbuvir is a nucleotide analog NS5B polymerase inhibitor while Velpatasvir is an NS5A inhibitor. Hepcvel Tablet is a new medicine used to treat hepatitis C. It is a combination pill containing sofosbuvir (sold separately as Sovaldi) plus Velpatasvir.
Each dose contains 400 mg sofosbuvir and 100 mg Velpatasvir. The medicines include the following inactive components: Copovidone, croscarmellose sodium, magnesium stearate, and microcrystalline cellulose. The drugs are film-coated with a coating material containing the following inactive ingredients: iron oxide red, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.
SOFOSBUVIR; VELPATASVIR (so fos’ bue veer; vel pat’ us veer) is an antiviral medicine. It is used with other medications to treat hepatitis C. It will not work for colds, flu, or other viral infections. This tablet may be used for other purposes; ask your health care provider or pharmacist if you have questions.
The combination of Sofosbuvir and Velpatasvir is used alone or with ribavirin (Copegus, Rebetol, and Ribasphere) to treat chronic hepatitis C (an ongoing viral infection that damages the liver). Sofosbuvir 400mg is in a class of antiviral medicines called nucleotide hepatitis C virus (HCV) NS5B polymerase inhibitors. Velpatasvir 100mg is in a group of antiviral drugs called HCV NS5A replication complex inhibitors. The combination of sofosbuvir and Velpatasvir works by stopping the virus that causes hepatitis C from spreading inside the body.
Hepcvel Tablet contains two direct-acting antiviral drugs that target different steps of the hepatitis C virus (HCV) lifecycle. Sofosbuvir is a nucleotide analog HCV polymerase inhibitor, meaning it blocks the polymerase enzyme which the virus must use to reproduce. Velpatasvir is an HCV NS5A replication complex inhibitor that interferes with another protein HCV uses to replicate.
The recommended dose of this medication is one tablet taken by mouth, once daily. It is commonly taken for 12 weeks. Velpatasvir – Sofosbuvir can be taken with food or on an empty stomach. If you vomit within 3 hours of taking medicine, take another dose of the drug. If it is longer than 3 hours since you have taken medicine, do not take another tablet. Continue with your regular dose schedule. Finish all this medication, even if you have started to feel better. Many things can affect the dose of drugs that a person needs, such as body weight, other medical conditions, and other medications.
Multiple clinical tests evaluated the safety and efficacy of Hepcvel. When taken with ribavirin, the most common side effects are:
- Anemia (low red blood cell count)
This is not an exhaustive list of all potential side effects of Hepcvel. These results are mild and nothing to worry about. Please tell your doctor if you experience any adverse reaction to the medication.
Hepcvel Tablet is a once-daily oral medication. A typical dose of Hepcvel contains 400mg of sofosbuvir and 100mg of Velpatasvir and can be taken with or without food. Do not start taking any medications without alerting your provider while on Hepcvel. Do not stop taking Hepcvel or change the dose of Hepcvel without talking to your provider. If you miss a dose, then call your healthcare provider or pharmacist. If you take too much Hepcvel, seek help at your local emergency room quickly.
Keep out of the reach of children. Store at room temperature below 30 degrees C (86 degrees F). Throw away any unused medication after the expiration date.
Most adults will recover from an acute hepatitis B infection without treatment. If the virus has been in the blood for more than 6 months, it is considered a permanent (or chronic) hepatitis B infection.
Sofosbuvir is used to treat Hepatitis C virus infection. The treatment response with Sofosbuvir (in conjunction with other drugs) varies based on baseline host and viral factors.
No. Sofosbuvir is a nucleotide polymerase inhibitor.
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Sofosbuvir and Velpatasvir
Sofosbuvir / Velpatasvir
Chronic hepatitis C virus (HCV) infection
28 tablets in 1 bottle
Sofosbuvir (400mg) + Velpatasvir (100mg)