Doxinate Tablet

Doxinate (Doxylamine Pyridoxine )

Doxylamine or doxylamine succinate is used for the short-term treatment of insomnia (difficulty falling or staying asleep). Doxinate Tablets also controls sneezing, runny nose, watery eyes, hives, skin rash, itching, and other symptoms of cold or allergy. It is also used for morning sickness (pregnancy related nausea-vomiting).

Doxinate belongs to a class of drugs called as antihistaminic. Doxylamine Pyridoxine acts by blocking the effects of the mainly chemical histamine and few others in the body, which are responsible for the symptoms of allergies, cold and morning sickness. It also causes drowziness and helps in falling a sleep.

Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5′-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).

Blurred vision, Confusion, Constipation, Convulsion, Diarrhoea, Abdominal pain, Dizziness, Drowsiness, Dry mouth, Shortness of breath, Difficulty in urination, Headache, Altered heart rate, Muscle pain, Muscle weakness, Restlessness, Skin rash, Tachycardia, Heart rate irregular, Vision disorder

Food : There is no data available. Please consult doctor before consuming the drug.
Alcohol : It may cause excessive drowsiness and calmness with alcohol.
Pregnancy : It may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The potential benefits may outweigh the risks. Please consult your doctor.
Lactation : Unknown. Human and animal studies are not available. Please consult your doctor.

Do not take Doxinate OD Tablet if you are allergic to it or to any other content in the medicine. Inform your doctor before taking the medicine:
• If you have glaucoma (raised pressure in the eye), asthma, bronchitis (inflammation of air passages), emphysema (blocking of air flow to the lungs) or other chronic lung diseases.
• If you have problems with urination or an enlarged prostate.
• If you are pregnant, planning to become pregnant or breast-feeding a baby.
Do not try strenuous exercise in hot weather, since doxylamine can decrease sweating. Do not drive or operate heavy machinery after taking this medicine as it may cause drowsiness.Do not take alcohol with this medication as it may increase drowsiness.Do not give the medicine to children less than 6 years of age.

Q. Is Doxylamine Pyridoxine a blood-thinner/anticholinergic/sleep aid?
Doxylamine is not a blood-thinner. But is does have anticholinergic property. It induces sleep and hence, is prescribed for short-term treatment of insomnia as a sleep aid.
Q. Is doxylamine safe?
Yes. Doxylamine Pyridoxine is relatively safe if used as recommended. In case of any side-effects, consult your doctor.
Q. Is doxylamine the same as diphenhydramine?
No. Doxylamine and diphenhydramine are two different drugs from the same class called antihistamines.
Q. Can I take doxylamine with ibuprofen, prednisone, pseudoephedrine, Zyrtec, citalopram, or Benadryl?
Yes. Doxylamine can be taken with ibuprofen, prednisone, pseudoephedrine, Zyrtec (cetrizine), citalopram, or Benadryl if prescribed by your doctor.
Q. Does Doxylamine Pyridoxine cause weight-gain, drowsiness, high blood pressure, dementia, diarrhea, tiredness, or Alzheimer’s disease?
Doxylamine may cause drowsiness, tiredness, diarrhea, or increase the blood pressure. However, it does not cause weight gain, dementia or Alzheimer’s disease.
Q. Can I take doxylamine succinate if I have high blood pressure?
Doxylamine Pyridoxine may cause increase in blood pressure if you already suffer from hypertension. It is advisable to consult your doctor before use.

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