Combunex 800 Tablet

Combunex 800 (Isoniazid 300 mg + Ethambutol 800)

Combunex 800 (Isoniazid 300mg + Ethambutol 800mg) Isoniazid is used in the prevention and treatment of tuberculosis (TB -a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It is always given in combination with other antituberculosis drugs. Ethambutol is used in the prevention, treatment and recurrence (second time treatment) of tuberculosis.

Combunex 800 (Isoniazid) is used in the prevention and treatment of tuberculosis (TB -a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It is always given in combination with other antituberculosis drugs. Ethambutol is used in the prevention, treatment and recurrence (second time treatment) of tuberculosis (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It is always given in combination with other antituberculosis drugs.

Isoniazid 300 mg belongs to a class of antituberculosis drugs. It suppresses the growth of tuberculosis causing bacteria (Mycobacterium tuberculosis). It interferes with the formation of the outer protective covering (cell wall) of the bacteria by inhibiting the synthesis of a chemical called mycolic acid an essential component of cell wall.

Ethambutol belongs to a class of anti-tuberculosis drugs. It suppresses the growth of tuberculosis causing bacteria (Mycobacterium tuberculosis). Ethambutol enters the growing bacteria and kills the bacteria by inhibiting an important enzyme arabinosyl tranferases involved in the formation of the outer protective covering of the bacteria called cell wall.

Toxic psychosis, Weakness, High blood sugar levels, Deficiency niacin., Anaemia, Nausea, Liver problems, Discomfort in the upper part of abdomen below the ribs, Abnormal brain function due to drug toxicity, Abnormal blood counts, Vomiting, Breast enlargement in men, Nerve problems in eyes, Constipation, Hypersensitivity reactions, Fits, Memory problems, Dry mouth, Numbness and pain in hands and feet, Severe skin reactions, Swelling of joints, Inflammation of pancreas

Abnormal liver function tests and very rarely liver failure., Numbness and tingling of hands and feet, Itching of skin, Nausea, Inflammation of liver, Vomiting, Skin rashes, Visual disturbances, Pale red raised itchy, High blood levels of uric acid, Loss of appetite, Color blindness, Abdominal pain and diarrhea, Eye pain), Numbness and pain in hands and feet due to nerve damage, Jaundice, Weaknes

• Do not take Combunex 800, if you have severe liver problems or if you have taken isoniazid in the past and it caused liver problems, fever, chills, joint pain, or severe allergic reaction.
• Contact your doctor immediately, if you experience symptoms such unusual tiredness (fatigue), weakness, feeling of discomfort (malaise), loss of appetite (anorexia), urge to vomit (nausea) or vomiting while taking isoniazid. It indicates that you are progressing towards liver damage.
• Do consult your doctor before taking Combunex 800 if you are aged above 35 years. The frequency of isoniazid related inflammation of liver (hepatitis) is higher in individuals older than 35 years of age. The doctor may advice measurement of blood levels of enzyme transferases before starting treatment with isoniazid.
•  Avoid drinking alcohol. It may increase your risk of liver damage while you are taking isoniazid.
• Do consult your doctor before taking Combunex 800, if you are pregnant or planning to become pregnant or are breastfeeding.
• Combunex 800 interacts with many drugs. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects.
• Do not stop taking isoniazid without consulting your doctor.
• If you forget to take a dose of Isoniazid, take it as soon as you remember. Do not double the dose to make up for the missed dose.