What is Powerpill?

What is sildenafil (generic of Viagra®)?
Sildenafil is also known as the generic of Viagra®, and it is the non branded version of the drug. It is cheaper than branded Viagra®, but no less effective for helping to treat erectile dysfunction. Sildenafil citrate is the active ingredient in both Viagra and generic of Viagra®.

What is tadalafil?

Generic of Cialis® is also known as tadalafil, and it is the non branded version of the drug. It is cheaper than branded Cialis, and can be taken as-need or daily to treat erectile dysfunction. Tadalafil is the active ingredient in both Cialis® and generic of Cialis®.

How do I take sildenafil or Tadalafil?
Sildenafil is an as-needed medication you can take when you want to be ready for sex. Here are some helpful tips:

  1. Test it solo first. Try your medication without a partner first so you see how it affects you/your body.

  2. Take at least 60 minutes before sex. Your medication stays in the body for approx. 4-6 hours.

  3. Works best on a close to empty stomach. Avoid fatty food and alcohol prior to using treatment.

  4. Arousal required. Sildenafil won’t automatically give you an erection if you’re not aroused, so start with foreplay to see the best results.

Important Safety Information for Generic of Viagra® & Cialis®

What is the FDA-approved use of sildenafil or Tadalafil?

Sildenafil is a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED).

Who should not use sildenafil or Tadalafil?

Do not use sildenafil if:

  • You are taking a class of medications called nitric oxide donors, including organic nitrates or organic nitrites in any form. Sildenafil can increase the blood pressure-lowering effect of nitrates.

  • You have a known allergy to sildenafil or Tadalafil.

  • You are taking a class of medications called guanylate cyclase (GC) stimulators, such as riociguat. Sildenafil can increase the blood pressure-lowering effect of these medications.

How should I take sildenafil or Tadalafil?

Sildenafil can be taken with or without food. Take about 30 minutes to 1 hour before anticipated sexual activity.

Do not take sildenafil more than once in a 24-hour period or within 24 hours of any other ED medications or PDE-5 inhibitors.

You should take the medication exactly as prescribed. If your symptoms are not improving or you have any questions about changing or stopping medication, reach out to your Ro-affiliated provider for guidance.

What should I tell my Alldaygeneric provider before using sildenafil or Tadalafil?

  • sildenafil or Tadalafil has certain drug interactions. It’s important to tell your Ro-affiliated provider all of the medications you are currently taking, including prescription, over-the-counter medications, vitamins, and herbal and dietary supplements.

Some medications to watch out for include

  • Nitrates, alpha-blockers, and antihypertensives: When these medications are taken with sildenafil, a sudden drop in blood pressure can occur.
  • CYP3A4 inhibitors, such as ritonavir, ketoconazole, itraconazole and erythromycin: These medications increase sildenafil levels in the blood stream, which can cause a sudden drop in blood pressure and prolonged erection.
  • It’s important to share your entire medical history with your provider. In particular, tell your provider if you have or have a past history of:

  • Cardiovascular risk that prevents you from partaking in sexual activity
  • Chest pain requiring nitroglycerin
  • Predisposition to priapism (painful erection that lasts >4 hours)
  • Ventricular outflow obstruction (e.g. aortic stenosis, idiopathic hypertrophic subaortic stenosis)
  • Severely impaired autonomic control of blood pressure
  • Myocardial infarction, stroke, or life-threatening arrhythmia 
  • Low or high blood pressure
  • Cardiac failure or coronary artery disease causing unstable angina
  • Anterior ischemic optic neuropathy (NAION) or a “crowded” optic disc.
  • Bleeding disorders or ulcers
  • Kidney or liver disease
  • Pulmonary hypertension
  • Retinitis pigmentosa

Withholding or providing inaccurate information about your health and medical history in order to obtain treatment may result in harm, including, in some cases, death.

What are the most serious side effects that I or a caregiver should monitor for when taking sildenafil or Tadalafil?

You or a caregiver should carefully monitor for these side effects, especially in the beginning of treatment.

  • Cardiac risk of sexual activity: ED medication should not be used by men for whom sexual activity is not advised because of their underlying cardiovascular status. 
  • Prolonged erections: Seek immediate emergency treatment for an erection lasting more than 4 hours.
  • Effects on the eye: Seek medical care and stop medication if you experience a sudden loss of vision in one or both eyes. Sudden loss of vision could be a sign of non arteritic anterior ischemic optic neuropathy (NAION).
  • Sudden hearing loss: Stop medication and seek prompt medical attention if you experience a sudden decrease or loss of hearing, which may be accompanied by ringing in the ears. 
  • Co-administering with alpha-blockers or other blood pressure-lowering drugs: If you are taking a medication to lower your blood pressure or taking an alpha-blocker, sildenafil may increase the blood-pressure-lowering effect, leading to a sudden drop in blood pressure. When starting sildenafil, monitor carefully for signs of low blood pressure, including dizziness, lightheadedness, or fainting.
  • Co-administering with ritonavir: If you are taking a medication called ritonavir at the same time as taking sildenafil, ritonavir can increase the amount of sildenafil in your system. Monitor for lowered blood pressure, fainting, and prolonged erection.
  • Combination with other PDE-5 inhibitors: Do not take sildenafil more than once in a 24-hour period or within 24 hours of any other ED medications or PDE-5 inhibitors.
  • Effects on bleeding: Sildenafil has no effect on bleeding time when taken alone or with aspirin; however, there have been reports of bleeding with the use of sildenafil. Tell your Ro-affiliated provider if you have a history of bleeding disorders or ulcers.
  • Sexually transmitted infections: Sildenafil does not protect against sexually transmitted diseases. Use safe sex practices.

What are the most common side effects of sildenafil or Tadalafil?

  • Headache
  • Flushing
  • Indigestion
  • Vision changes
  • Nasal congestion
  • Back pain
  • Muscle pain
  • Nausea
  • Dizziness
  • Rash

This information is not comprehensive. Please see the full Prescribing Information for complete safety information.

Powerpill (Available Brands)

Viafil 25mg Tablet
Viafil 50mg Tablet
Viafil 100mg Tablet
Viafil 150mg Tablet
Viafil 200mg Tablet
Ciasel 10mg Tablet
Ciasel 20mg Tablet
Ciasel 40mg Tablet
Ciasel 60mg Tablet
Ciasel 80mg Tablet