Difference between Vardenafil vs Tadalafil: Everything Explained

Vardenafil vs Tadalafil

Millions of men across the world, suffer from sexual problems like improper penile erection, early ejaculation, lack of enough sexual drive, etc. Such medical problems are commonly termed as erectile dysfunction. Thankfully, there are multiple medications like Sildenafil, Tadalafil, Vardenafil, Avanafil, etc; available to cure such medical conditions. 

Tadalafil vs Vardenafil: Key Differences Explained

Parameters Tadalafil  Vardenafil
Nature of Salt phosphodiesterase type 5 inhibitor, phosphodiesterase type 5 (PDE5)
Erection Duration 17 to18 hours 8 hours
Mechanism of Action  Works by inhibiting the effect of PDE5. This inhibition leads to penile erection due to the inflow of blood into the area. Being a phosphodiesterase (PDE) inhibitor, it works by increasing blood flow to the penis; upon receiving sexual stimulation. 
Dosage strengths available 5 mg, 10 mg, 20 mg, 40 mg, and 60 mg 10 mg, 20 mg, 40 mg, and 60 mg
Timing of Consumption 30 minutes before the sexual act 25 to 60 minutes before sex prior sex
Dissolution duration 30 minutes 30 to 60  minutes 
Side effects The most common potential adverse effect of using tadalafil are back pain, burping acid reflux, headache, stomach discomfort or pain, indigestion, muscle aches, flushing, and stuffy and runny nose.  Headache, Flushing (reddening of the face, ears, neck, and trunk), Dizziness, Back pain, Nausea, Nasal congestion (stuffy nose), Dyspepsia, Sinus inflammation, Flu-like symptoms, Increased creatine level in blood. 
Storage requirement 20°C – 25°C 15° to 30°C

FAQs about the difference between Vardenafil and Tadalafil

Tadalafil is capable of offering a much longer erection duration. Vardenafil is more selective than sildenafil and tadalafil to PDE5, which again means a lower dose is needed with potentially less side effects. Tadalafil is very specific for PDE5 and is also very specific for the enzyme PDE11.

Both of the medicines belong to the same class of drug, i,e PDE5 inhibitor and has the same kind of mechanism of work for the same set of purpose. Yet they are two different pharmaceutical ingredients and project different intensity in the results, and have different interactions with other drugs.

Currently, there is no scientific evidence that vardenafil, tadalafil or any other medications used to treat erectile dysfunction are physically addictive.

Tadalafil is capable of offering a much longer erection duration. Vardenafil is more selective than sildenafil and tadalafil to PDE5, which again means a lower dose is needed with potentially less side effects. Tadalafil is very specific for PDE5 and is also very specific for the enzyme PDE11.

Both Vardenafil and Tadalafil are strong prescribed medications that can cause serious side effects if consumed without a thorough medical consultation. Hence a detailed diagnosis is advised before finalizing either of these two pharmaceutical drugs to cure erectile dysfunction.

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