Sildenafil or Sildenafil Citrate is one of the most popular and effective generic medications, known across the world. It has already generated remarkable results and sees high demand in the international market, round the year. Let us check out some of the most important aspects of this medication. 

What is Sildenafil?

Sildenafil or Sildenafil Citrate is quite a popular selective phosphodiesterase type 5 inhibitor (PDE5 inhibitor) i,e vasodilatation pharmaceutical drug. It acts by inhibiting cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). In simplest of terms, it boosts up the blood vessels and allows greater blood circulation to the penile area in male bodies, causing a desired erection for successful intercourse and sufficient sexual pleasure.

Everything about Sildenafil and How it Helps Men in Lasting Longer in Bed?

Top 5 Most Important Facts About Sildenafil 

#1 What is Sildenafil used for? 

It is associated with the treatments of Erectile Dysfunction (ED) or impotency in men, NYHA Functional Class II-III Pulmonary arterial hypertension (PAH), and Premature Ejaculation (PE). As a phosphodiesterase type 5 inhibitor, It has proven to have successfully projected a penial erection for about 4 hours. 

#2 How does Sildenafil work?

Sildenafil has no direct relaxant effect on isolated human corpus cavernosum; but increases the effect of nitric oxide by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for the degradation of cGMP in the corpus cavernosum. When asexual stimulation causes the local release of Nitric Oxide, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in effortless muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil has no effect in the absence of sexual stimulation. 

#3 How long does Sildenafil take to come into effect? 

Sildenafil is quite an advantageous medication. This medication can be consumed some 30 to 60 minutes before the sexual act to have a desirable penial erection. 

#4 How long will its results last? 

Sildenafil is quite a popular choice for getting a penial erection. It is capable of demonstrating its results for up to 4 hours duration. 

#5 What is the most common dosage for Sildenafil Citrate?

Sildenafil tablets for erectile dysfunction come in different strengths or powers ranging from 25 mg to 100 mg. The usual dose power is 50 mg when you need it. The dose power can be increased to 100 mg or decreased to 25 mg depending on its effect. For a further understanding, read Everything about How to Take Sildenafil Tablets and How Often You Should Take It? and Taking How Much Sildenafil is Too Much? Explained. 

Does Sildenafil make you last longer? 

Sildenafil or Sildenafil Citrate is an FDA-approved medication against erectile dysfunction in men. It has already been tried by millions of men worldwide and has generated great results for patients. In general, it is supposed to offer penile erections for up to 4 to 6 hours duration, approximately, in patients who lack enough blood flow in the blood vessels near the penile area.

Sildenafil is quite an advantageous medication when it comes to getting a penile erection. This medication can be consumed some 30 to 60 minutes before the sexual act in order to have a desirable penial erection. 

When it comes to observing the onset time of erections after sildenafil (50 mg) or placebo dosing following some visual sexual stimulation (VSS), it can be said that less than 60% penile rigidity is achieved in 70 minutes. The duration of ‘hard enough for penetration’, and ‘fully hard erections’, is at 2 and 4 hours respectively, after sildenafil (100 mg) or placebo dosing. However, alcohol and high-fat content meals should be avoided while consuming this medication; as they can slow down its effects. 

Preventive Measures to take when taking Sildenafil Tablets to Make You Last Longer 

Patients need to reconsider their lifestyle habits and try to include the following changes:

• Quit smoking.
• Minimize daily stress.
• Manage weight through a healthy diet and regular activities.
• Participate in daily exercise and physical activity.
• Reduce or eliminate alcohol intake.

What if Sildenafil does not work?

Sildenafil Citrate might not work as one of the most effective treatments for erectile dysfunction, for various reasons, like those mentioned below: 

• Using Sildenafil incorrectly
• Taking a lower dose 
• Using Sildenafil to treat ED that’s caused by something other than poor blood flow 
• Interventions with other drugs (for further understanding read Everything about Sildenafil Interactions with other Drugs) 

Also, in addition to medical interventions, it’s important to address lifestyle factors that play a role in ED. Some common factors that can lead to conditions affecting blood circulation include:

• Lack of daily exercise 
• Smoking addiction 
• Excessive mental stress
• Drinking alcohol
• Substance abuse 

Hence patients should not panic or overdose in case a Silenafil tablet does not offer desirable results. Rather, they should always consult a licensed medical professional for the much-required guidance in such a scenario. One may consult with a urologist and pick from several other options to treat erectile dysfunction, as mentioned below: 

• Erectile dysfunction pump (penis or vacuum pump)
• Penile injections
• Surgery for an inflatable penile prosthesis
• Therapy for emotional, psychological, and relationship issues related to ED
• Suppositories (Alprostadil)

 

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